Interim results from two phase 1 trials demonstrate progress in the use of chimeric antigen receptor (CAR) T cell therapy for recurrent glioblastoma (GBM).

Induction of Rhoj in endothelial cells stimulates profibrotic vascular intussusception that hinders lung regeneration in mice.

The PRDM1-S/SGK1 axis and AP-1/IRF epigenetic priming are drivers of Treg dysfunction in multiple sclerosis and other autoimmune diseases.

GLUT10 enhances glucose uptake in CD8+ T cells to improve antitumor function.

Combining MEK/CDK4/6 inhibitors with nanoparticle delivery of STING/TLR4 agonists leads to T cell–mediated control of pancreatic tumors in mice.

A cyberterrorism charge in Pakistan connected to riots in the UK illustrates how authorities are reaching across borders to tackle disinformation, but bringing overseas suspects to justice won't always be possible

The James Webb Space Telescope has spotted six strange worlds the size of planets that formed like stars – and the smallest may be building its own miniature solar system

An AI-powered model found that approaching intersections more slowly could lower yearly US carbon emissions by up to around 123 million tonnes

Computers made from DNA have previously only been able to store information or perform computations on it – now a new device can do both

The Milky Way may be home to strange black holes from the first moments of the universe, and the best candidates are the three closest black holes to Earth

Radio astronomers teamed up with SpaceX to find a promising solution for helping expensive telescopes avoid interference from thousands of Starlink satellites

Astronomers have identified patterns within the motion of stars stretching across the Milky Way, hinting at the presence of a vast wave

Researchers trained a polymer gel to play the computer game Pong by passing electric current through it and measuring the concentration of ions

After a star explodes, the resulting supernova remnant collapses in on itself and could begin the cycle again, creating generations of stars enriched with heavy elements

Sam Howell tells New Scientist why NASA is so keen to visit Jupiter’s fourth-largest moon, Europa, and how the mission could help us figure out the likelihood of life elsewhere in the cosmos

The books, TV, games and more that New Scientist staff have enjoyed this week

After 25 years in orbit, the Chandra X-ray Observatory is under threat. We need to protect this monument to human ingenuity, argues Chanda Prescod-Weinstein

After their initial training phase, AI algorithms can’t update and learn from new data, meaning tech companies have to keep training new models from scratch

Past observations have indicated that the icy moon of Jupiter has a vast subsurface ocean. Launching in October, NASA’s Europa Clipper will go there in search of evidence that it could support life

Immunological imprinting to the SARS-CoV-2 spike protein by memory B cells is redirected toward Omicron sublineages after repeated BA.5 exposures.